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Human IL-4 protein

CAT: 0749-PRP1959-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0749-PRP1959-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immune responses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13. IL-4, originally designated as B-cell growth factor-1 (BSFl), is described in the supernatant of activated EL-4 thymoma cells as a factor that can co-stimulate B-cells activated with submitogenic concentrations of anti-IgM.
Description
Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immune responses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13. IL-4, originally designated as B-cell growth factor-1 (BSFl), is described in the supernatant of activated EL-4 thymoma cells as a factor that can co-stimulate B-cells activated with submitogenic concentrations of anti-IgM.
Gene ID
3565
Accession Number
P05112
Applications
No tag
Purity
> 96 % as determined by SDS-PAGE
Activity
Measured in a cell proliferation assay using TF-1. The ED50 for this effect is typically 0.144 ng/mL. The specific activity of recombinant Human IL4 is approximately >6.94 x 106IU/mg
Molecular Formula
15.1 kDa
Molecular Weight
15.1 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: <1 EU per μg of the protein by the LAL metho
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles
Protein Length
The recombinant Human IL-4 consists of 129 amino acids and predicts a molecular mass of 15.1 kDa.
Formulation
Lyophilized from sterile 20 mM Tris-HCl, 150 mM NaCl, pH 7.4.
Applications Notes
Human
Other Product Names
Human IL-4 protein、IL-4
Recommended Usage
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions
Preparation
E.coli
AA Sequence
Amino acid sequence derived from Human IL-4 (His25-Ser153) (P05112-1) was expressed.

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