WIZ degrader 1

WIZ degrader 1

• CAS Number: 2839552-68-8
• UNSPSC Description: WIZ degrader 1 (Compound 141) is a degrader for widely interspaced zinc finger motifs (WIZ) with an AC50 of 2 nM. WIZ degrader 1 induces the expression of fetal hemoglobin (HbF) with an EC50 of 6 mM. WIZ degrader 1 is used in research of inherited blood disorders[1].
• Target Antigen: Histone Methyltransferase
• Type: Reference compound
• Related Pathways: Epigenetics
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/wiz-degrader-1.html
• Smiles: FC1(F)CCC(CN2CC[C@@H](CC3=CC4=C(N5CCC(NC5=O)=O)C=NN4C=C3)C[C@@H]2C)CC1
• Molecular Weight: 473.56
• References & Citations: [1]BONAZZI S, et al., Pyrazolopyridine Derivatives and Uses thereof. US20240158374A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported