WIZ degrader 1

• UNSPSC Description:

  WIZ degrader 1 (Compound 141) is a degrader for widely interspaced zinc finger motifs (WIZ) with an AC50 of 2 nM. WIZ degrader 1 induces the expression of fetal hemoglobin (HbF) with an EC50 of 6 mM. WIZ degrader 1 is used in research of inherited blood disorders[1].

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/wiz-degrader-1.html

• Smiles:

  FC1(F)CCC(CN2CC[C@@H](CC3=CC4=C(N5CCC(NC5=O)=O)C=NN4C=C3)C[C@@H]2C)CC1

• Molecular Weight:

  473.56

• References & Citations:

  [1]BONAZZI S, et al., Pyrazolopyridine Derivatives and Uses thereof. US20240158374A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2839552-68-8