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IKZF1-degrader-2

CAT: 0804-HY-160533Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-160533Size:1 Each
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Description
IKZF1-degrader-2 (Compound 3) is an IKZF1 molecular glues degrader. IKZF1-degrader-2 has anticancer activity and low toxicity[1].
CAS Number
2915330-86-6
UNSPSC
12352005
Target
IKZF Family; Molecular Glues
Type
Reference compound
Related Pathways
Immunology/Inflammation; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ikzf1-degrader-2.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(C(OC2)=C1)N(CC3)[C@]2([H])CN3CC(C=C4)=CC=C4COC5=C6C(C(N([C@@H]7C(NC(CC7)=O)=O)C6)=O)=CC(F)=C5
Molecular Formula
C33H30FN5O5
Molecular Weight
595.62
References & Citations
[1]Fu LQ, et al. Isoindolinone compound and use thereof. WO2023025136A1. 2023-03-02.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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