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STING-IN-15

CAT: 0931-T207666-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207666-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2912492-05-6
Target
STING
Related Pathways
Immunology/Inflammation
Bioactivity
STING-IN-15 (compound 66) is a potent STING inhibitor, effectively suppressing human and mouse STING with IC50 values of 116 nM and 96.3 nM, respectively. In the REX1 D18N mouse model, STING-IN-15 significantly reduces tissue damage and inflammation.
Smiles
N(C(NC=1C=C2C(=CC1)OC(F)(F)O2)=O)C=3C=4C(NC3)=CC=C(/C=C/CC#N)C4
Molecular Formula
C20H14F2N4O3
Molecular Weight
396.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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