STING-IN-15

• Target:

  STING

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  STING-IN-15 (compound 66) is a potent STING inhibitor, effectively suppressing human and mouse STING with IC50 values of 116 nM and 96.3 nM, respectively. In the REX1 D18N mouse model, STING-IN-15 significantly reduces tissue damage and inflammation.

• Smiles:

  N(C(NC=1C=C2C(=CC1)OC(F)(F)O2)=O)C=3C=4C(NC3)=CC=C(/C=C/CC#N)C4

• Molecular Formula:

  C20H14F2N4O3

• Molecular Weight:

  396.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2912492-05-6