CDK2 degrader 3

• UNSPSC Description:

  CDK2 degrader 3 can selectively degrade CDK2 and has anti-tumor activity[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk2-degrader-3.html

• Smiles:

  O=C1N(C2CCCC2)C3=NC(NC4=C(C=C(C=C4)S(NCCO[C@H]5CC[C@@H](CC5)CN6CCC(C7=CC8=NC=C(N9C(NC(CC9)=O)=O)N8C=C7)CC6)(=O)=O)C)=NC=C3C=C1Cl

• Molecular Weight:

  885.47

• References & Citations:

  [1]Nicholas Kwiatkowski, et al. CDK2 Heterobifunctional Degraders Co-Degrade CDK2 and Cyclin E Resulting in Efficacy in CCNE1-Amplified and Overexpressed Cancers. KYMERA. 2024.OCTOBER 23.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2862772-71-0