CDK2 degrader 3

CDK2 degrader 3

• CAS Number: 2862772-71-0
• UNSPSC Description: CDK2 degrader 3 can selectively degrade CDK2 and has anti-tumor activity[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cdk2-degrader-3.html
• Smiles: O=C1N(C2CCCC2)C3=NC(NC4=C(C=C(C=C4)S(NCCO[C@H]5CC[C@@H](CC5)CN6CCC(C7=CC8=NC=C(N9C(NC(CC9)=O)=O)N8C=C7)CC6)(=O)=O)C)=NC=C3C=C1Cl
• Molecular Weight: 885.47
• References & Citations: [1]Nicholas Kwiatkowski, et al. CDK2 Heterobifunctional Degraders Co-Degrade CDK2 and Cyclin E Resulting in Efficacy in CCNE1-Amplified and Overexpressed Cancers. KYMERA. 2024.OCTOBER 23.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported