CDK2 degrader 8

• Description:

  CDK2 degrader 8 (Compound1) is a CDK2 degrader. CDK2 degrader 8 shows potential anti-tumor activity by targeting CDK2. CDK2 degrader 8 can be used for the study of solid tumors (breast cancer, triple negative breast cancer, ovarian serous cystadenocarcinoma) and liquid tumors (diffuse large B-cell lymphoma, acute myelogenous leukemia) associated with abnormal CDK2 function[1].

• UNSPSC:

  12352005

• Target:

  CDK

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Smiles:

  FC(F)(OC1=CC=C(C2=NN=C(O2)NC3(CC3)C4=CC(Cl)=C5CN(C(C5=C4)=O)C6CCC(NC6=O)=O)C=C1)F

• Molecular Formula:

  C25H19ClF3N5O5

• Molecular Weight:

  561.90

• References & Citations:

  [1]FASCHING, et al. Cyclopropyl and 1,3,4-Oxadiazole Compounds That Mediate Protein Degradation and Methods of Use Thereof. WO 2025/181261 A1. World Intellectual Property Organization (WIPO) . 04 September 2025.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3099145-52-2]