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CDK2 degrader 7

CAT: 0013-GTR19272867-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272867-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK2 degrader7 is an orally active CDK2 degrader with DC50 values of 13 nM in MKN1 cells and 17 nM in TOV21G cells. It induces G1 phase arrest in MKN1 cells and achieves tumor suppression in the HCC1569 (CCNE1 amplified) xenograft model. CDK2 degrader7 is utilized in research on CCNE1 amplification-type cancers.
CAS Number
3030279-55-8
Smiles
C (F) (F) (F) C=1C (=NC (NC2=C (F) C=C (S (N[C@H]3[C@@H] (F) CN (CC4CCN (CC4) C5=C (F) C=C (C=C5) C6C (=O) NC (=O) CC6) CC3) (=O) =O) C=C2) =NC1) N7C[C@@] (C) (O) CCC7
Molecular Formula
C39H46F6N8O5S
Molecular Weight
852.9
Storage Conditions
-20°C
Notes
For research use only.

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