NS 1738

CAT: 0804-HY-12151-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-12151-01Size:5 mg

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Description

NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nAChR, with respect to positive modulation of α7 nAChR (EC50=3.4 μM in oocyte experiments) .

CAS Number

501684-93-1

Product Name Alternative

NSC 213859

UNSPSC

12352005

Hazard Statement

H319

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/NS_1738.html

Purity

99.32

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(NC1=CC(C(F)(F)F)=CC=C1Cl)NC2=CC(Cl)=CC=C2O

Molecular Formula

C14H9Cl2F3N2O2

Molecular Weight

365.13

Precautions

H319

References & Citations

[1]Timmermann DB, et al. An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo. J Pharmacol Exp Ther. 2007 Oct;323 (1) :294-307.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Alternative Products

Catalog	Name
460983-01	NS 1738
A17079-100	NS 1738 100mg
A17079-50	NS 1738 50mg
A17079-5	NS 1738 5mg
A17079-25	NS 1738 25mg

NS 1738

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