NS-2710

• Description:

  NS-2710 is a high-efficacy GABAAα3 agonist with a Ki of 9.2 nM. NS-2710 can be used for anxiety research[1].

• UNSPSC:

  12352005

• Target:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ns-2710.html

• Purity:

  99.21

• Solubility:

  DMSO : 13.16 mg/mL (ultrasonic)

• Smiles:

  C/C(C1=CC=C2C(N=CN2C3=CC=CC(C4=CC=CN=C4)=C3)=C1)=N\OCC

• Molecular Formula:

  C22H20N4O

• Molecular Weight:

  356.42

• References & Citations:

  [1]John R Atack. GABAA receptor subtype-selective modulators. I. α2/α3-selective agonists as non-sedating anxiolytics. Curr Top Med Chem. 2011;11 (9) :1176-202.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  184220-36-8