NS-638

• Description :

  NS-638 is a small nonpeptide molecule with Ca2+-channel blocking properties. K+-stimulated intracellular Ca2+-elevation is blocked with an IC50 value of 3.4 μM.

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  Calcium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/NS-638.html

• Concentration :

  10mM

• Purity :

  99.84

• Solubility :

  DMSO : ≥ 34 mg/mL

• Smiles :

  NC1=NC2=CC(C(F)(F)F)=CC=C2N1CC3=CC=C(Cl)C=C3

• Molecular Formula :

  C15H11ClF3N3

• Molecular Weight :

  325.72

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]M?ller A, et al. Pharmacological profile and anti-ischemic properties of the Ca (2+) -channel blocker NS-638. Neurol Res. 1995 Oct;17 (5) :353-60.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  L-type calcium channel

• CAS Number :

  [150493-34-8]