Cyclopropaneacetamide-Exatecan

• Description :

  Cyclopropaneacetamide-Exatecan is an Exatecan (HY-13631) analogue and an ADC Cytotoxin. Cyclopropaneacetamide-Exatecan can be used to synthesize ADC molecules for cancer research[1].

• UNSPSC :

  12352203

• Target :

  ADC Payload; Topoisomerase

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cyclopropaneacetamide-exatecan.html

• Concentration :

  10mM

• Purity :

  99.60

• Solubility :

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O[C@@H](C1CC1)C(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O

• Molecular Formula :

  C29H28FN3O6

• Molecular Weight :

  533.55

• References & Citations :

  [1]Ying Hua, et al. Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof. Patent WO2020063673A1. 2020-04-02.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Camptothecins

• CAS Number :

  [2414254-36-5]