Decyclohexanamine-Exatecan

• Description :

  Decyclohexanamine-Exatecan (compound a) is a Camptothecin derivative, with a structure containing Exatecan (HY-13631), which can be used as a ADC cytotoxin[1].

• CAS Number :

  [2505045-51-0]

• UNSPSC :

  12352005

• Target :

  ADC Payload; Topoisomerase

• Type :

  Reference compound

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/decyclohexanamine-exatecan.html

• Purity :

  98.92

• Solubility :

  DMSO : ≥ 32 mg/mL

• Smiles :

  CC[C@@]1(C2=C(COC1=O)C(N3C(C(C(C3)=CC4=C5)=NC4=CC(F)=C5C)=C2)=O)O

• Molecular Formula :

  C21H17FN2O4

• Molecular Weight :

  380.37

• References & Citations :

  [1]Ravi Chari, et al. Camptothecin derivatives. Patent WO2020219287 A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Camptothecins