(9R) -Exatecan

• Description:

  (9R) -Exatecan (DX8951f) is the (1R,9S) stereoisomer of Exatecan (HY-13631) . Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.

• Product Name Alternative:

  (9R) -DX8951f

• UNSPSC:

  12352005

• Target:

  ADC Payload; Drug Derivative; Topoisomerase

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Others

• Field of Research:

  Cancer

• Smiles:

  N[C@@H]1C2=C3C(C(N4C3)=CC([C@@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62

• Molecular Formula:

  C24H22FN3O4

• Molecular Weight:

  435.45

• Shipping Conditions:

  Room temperature

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• CAS Number:

  [2489613-17-2]