Exatecan

• Target:

  ADC Cytotoxin|||Topoisomerase

• Related Pathways:

  Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Purity:

  0.9996

• Bioactivity:

  Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 ?M (0.975 ?g/mL) .Exatecan has antitumor activity and may be used in cancer research.

• Smiles:

  N[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6

• Molecular Formula:

  C24H22FN3O4

• Molecular Weight:

  435.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  171335-80-1