Exatecan

• Target:

  ADC Cytotoxin|||Topoisomerase

• Related Pathways:

  Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Purity:

  0.9996

• Bioactivity:

  Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 ?M (0.975 ?g/mL) .Exatecan has antitumor activity and may be used in cancer research.

• Smiles:

  N[C@@H]1C2=C3C (C=4N (C3) C (=O) C5=C (C4) [C@] (CC) (O) C (=O) OC5) =NC=6C2=C (CC1) C (C) =C (F) C6

• Molecular Formula:

  C24H22FN3O4

• Molecular Weight:

  435.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  171335-80-1