BF-168

• Description:

  BF-168, a candidate probe for PET, is found to specifically recognize both neuritic and diffuse plaques, with a Ki of 6.4 nM for Aβ1-42.

• UNSPSC:

  12352005

• Target:

  Amyloid-β

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/BF-168.html

• Purity:

  99.68

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  CNC1=CC=C(/C=C/C2=NC3=CC=C(OCCF)C=C3O2)C=C1

• Molecular Formula:

  C18H17FN2O2

• Molecular Weight:

  312.34

• References & Citations:

  [1]Okamura N, et al. Styrylbenzoxazole derivatives for in vivo imaging of amyloid plaques in the brain. J Neurosci. 2004 Mar 10;24 (10) :2535-41.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [634911-47-0]