CB 168

• UNSPSC Description:

  CB 168 is a potent and selective aminoacyl-sulfamoyl aryltetrazole inhibitor targeting isoleucyl-tRNA synthetase (IleRS)[1].

• Target Antigen:

  Aminoacyl-tRNA Synthetase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cb-168.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC[C@H](C)[C@H](N)C(NS(OC[C@H]([C@H]([C@H]1O)O)O[C@H]1CCN2N=C(C3=CC=CC=C3)N=N2)(=O)=O)=O

• Molecular Weight:

  498.55

• References & Citations:

  [1]De Ruysscher D, et al. Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase. Bioorg Med Chem. 2020 Aug 1;28(15):115580.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1241942-59-5