CB 168

• Description :

  CB 168 is a potent and selective aminoacyl-sulfamoyl aryltetrazole inhibitor targeting isoleucyl-tRNA synthetase (IleRS) [1].

• UNSPSC :

  12352005

• Target :

  Aminoacyl-tRNA Synthetase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/cb-168.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC[C@H](C)[C@H](N)C(NS(OC[C@H]([C@H]([C@H]1O)O)O[C@H]1CCN2N=C(C3=CC=CC=C3)N=N2)(=O)=O)=O

• Molecular Formula :

  C20H30N6O7S

• Molecular Weight :

  498.55

• References & Citations :

  [1]De Ruysscher D, et al. Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase. Bioorg Med Chem. 2020 Aug 1;28 (15) :115580.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1241942-59-5]