MARCKS Peptide(151-175), Phosphorylated

• UNSPSC Description:

  MARCKS Peptide(151-175), Phosphorylated is a phosphorylated peptide corresponding to the basic effector domain of myristoylated alanine-rich protein kinase C substrate protein (MARCKS). Phosphorylation of MARCKS Peptide (151-175) reverses its inhibition of phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2)[1].

• Target Antigen:

  MARCKS

• Type:

  Peptides

• Related Pathways:

  Cytoskeleton

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/marcks-peptide-151-175-phosphorylated.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H](N)CCCCN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CC2=CC=CC=C2)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)CCCCN)=O)CCCCN)=O)COP(O)(O)=O)=O)=O)CCCCN)=O)CC(C)C)=O)CO)=O)=O)CC3=CC=CC=C3)=O)COP(O)(O)=O)=O)=O)CCCCN)=O)CC4=CC=CC=C4)=O)COP(O)(O)=O)=O)CC5=CC=CC=C5)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CCCCN

• Molecular Weight:

  3320.70

• References & Citations:

  [1]Glaser M, et al. Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains..J Biol Chem. 1996 Oct 18;271(42):26187-93.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported