(5-Cl) -Exatecan

CAT: 0804-HY-160806Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-160806Size:1 Each

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Description

(5-Cl) -Exatecan (compound 1-5) is a potent DNA topoisomerase inhibitor used in cancer research. (5-Cl) -Exatecan is an ADC Cytotoxin[1].

CAS Number

2813268-66-3

UNSPSC

12352005

Target

ADC Payload; Topoisomerase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-cl-exatecan.html

Smiles

N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(Cl)=C(C)C(CC1)=C62

Molecular Formula

C24H22ClN3O4

Molecular Weight

451.90

References & Citations

[1]Haijun Tian, et al. Antibody drug conjugate, and preparation method therefor and use thereof. WO2022253035A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Camptothecins

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