(S)-Seco-Duocarmycin SA
CAT:
804-HY-129356A-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(S)-Seco-Duocarmycin SA
- CAS Number: 152785-82-5
- UNSPSC Description: (S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates[1].
- Target Antigen: ADC Cytotoxin; DNA Alkylator/Crosslinker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/s-seco-duocarmycin-sa.html
- Purity: 99.0
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: ClC[C@H]1C2=C(C=C(O)C3=C2C=C(C(OC)=O)N3)N(C(C4=CC5=CC(OC)=C(OC)C(OC)=C5N4)=O)C1
- Molecular Weight: 513.93
- References & Citations: [1]Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported