Seco-Duocarmycin SA

Seco-Duocarmycin SA

• CAS Number: 144667-38-9
• UNSPSC Description: Seco-Duocarmycin SA is a DNA alkylator, and is used as an ADC cytotoxin[1].
• Target Antigen: ADC Cytotoxin; DNA Alkylator/Crosslinker
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/seco-duocarmycin-sa.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC2=C3C(N(C(C(N4)=CC5=C4C(OC)=C(OC)C(OC)=C5)=O)CC3CCl)=CC(O)=C2N1)OC
• Molecular Weight: 513.93
• References & Citations: [1]Lutz F. Tietze, et al. A Concise and Efficient Synthesis of seco-Duocarmycin SA. European Journal of Organic Chemistry 2003 (3), 562-566.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported