Seco-Duocarmycin SA

• UNSPSC Description:

  Seco-Duocarmycin SA is a DNA alkylator, and is used as an ADC cytotoxin[1].

• Target Antigen:

  ADC Cytotoxin; DNA Alkylator/Crosslinker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/seco-duocarmycin-sa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC2=C3C(N(C(C(N4)=CC5=C4C(OC)=C(OC)C(OC)=C5)=O)CC3CCl)=CC(O)=C2N1)OC

• Molecular Weight:

  513.93

• References & Citations:

  [1]Lutz F. Tietze, et al. A Concise and Efficient Synthesis of seco-Duocarmycin SA. European Journal of Organic Chemistry 2003 (3), 562-566.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  144667-38-9