Seco Rapamycin

Seco Rapamycin

• CAS Number: 147438-27-5
• UNSPSC Description: Seco Rapamycin (Secorapamycin A) is the ring-opened product of Rapamycin. Seco-rapamycin is reported not to affect the mTOR function[1].
• Target Antigen: Drug Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/Seco_Rapamycin.html
• Purity: 81.12
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@H]1N(C(C([C@@]2(O)[C@H](C)CC[C@@H](C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C([C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(/C=C/[C@H](C)C[C@H]3C[C@@H](OC)[C@H](O)CC3)=O)=O)O2)=O)=O)CCCC1)O
• Molecular Weight: 914.17
• References & Citations: [1]Paine MF, et al. Identification of a novel route of extraction of sirolimus in human small intestine: roles ofmetabolism and secretion. J Pharmacol Exp Ther. 2002 Apr;301(1):174-86.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported