FXIa-IN-14

FXIa-IN-14

• CAS Number: 2423992-72-5
• UNSPSC Description: FXIa-IN-14 (Compound 14c) is a FXIa inhibitor with an IC50 value of 15 nM[1].
• Target Antigen: Factor Xa
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/fxia-in-14.html
• Solubility: 10 mM in DMSO
• Smiles: ClC1=CC2=C(NC(C=C2CN(C([C@H](CC3=CC=C(NC(C4C(C)C4)=O)C=C3)NC(C5=CC=C(C(O)=O)S5)=O)=O)C)=O)C=C1
• Molecular Weight: 621.10
• References & Citations: [1]Wang Y, et al. Design, synthesis and biological evaluation of 6-chloro-quinolin-2-one derivatives as novel FXIa inhibitors. Bioorg Med Chem Lett. 2024 Jan 9;99:129610.|[2]Wang Y, et al. Design, synthesis and biological evaluation of 6-chloro-quinolin-2-one derivatives as novel FXIa inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 99: 129610.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported