FXIa-IN-14
CAT:
804-HY-157547
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FXIa-IN-14
- CAS Number: 2423992-72-5
- UNSPSC Description: FXIa-IN-14 (Compound 14c) is a FXIa inhibitor with an IC50 value of 15 nM[1].
- Target Antigen: Factor Xa
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/fxia-in-14.html
- Solubility: 10 mM in DMSO
- Smiles: ClC1=CC2=C(NC(C=C2CN(C([C@H](CC3=CC=C(NC(C4C(C)C4)=O)C=C3)NC(C5=CC=C(C(O)=O)S5)=O)=O)C)=O)C=C1
- Molecular Weight: 621.10
- References & Citations: [1]Wang Y, et al. Design, synthesis and biological evaluation of 6-chloro-quinolin-2-one derivatives as novel FXIa inhibitors. Bioorg Med Chem Lett. 2024 Jan 9;99:129610.|[2]Wang Y, et al. Design, synthesis and biological evaluation of 6-chloro-quinolin-2-one derivatives as novel FXIa inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 99: 129610.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported