FXIa-IN-14

• UNSPSC Description:

  FXIa-IN-14 (Compound 14c) is a FXIa inhibitor with an IC50 value of 15 nM[1].

• Target Antigen:

  Factor Xa

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/fxia-in-14.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC2=C(NC(C=C2CN(C([C@H](CC3=CC=C(NC(C4C(C)C4)=O)C=C3)NC(C5=CC=C(C(O)=O)S5)=O)=O)C)=O)C=C1

• Molecular Weight:

  621.10

• References & Citations:

  [1]Wang Y, et al. Design, synthesis and biological evaluation of 6-chloro-quinolin-2-one derivatives as novel FXIa inhibitors. Bioorg Med Chem Lett. 2024 Jan 9;99:129610.|[2]Wang Y, et al. Design, synthesis and biological evaluation of 6-chloro-quinolin-2-one derivatives as novel FXIa inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 99: 129610.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2423992-72-5