Products for Research Use Only
RegisterLogin

FXIa-IN-6

CAT: 0804-HY-145349Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-145349Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most of the relevant serine proteases (Ki = 0.3 nM) .
CAS Number
1551459-37-0
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fxia-in-6.html
Solubility
10 mM in DMSO
Smiles
COC(NC1=CC=C(C2=CC=NC([C@](N3C(C=C(C4=C(C(Cl)=CC=C4F)F)CC3)=O)([H])CCC[C@H](C(N5)=O)C)=C2)C5=C1)=O
Molecular Formula
C31H29ClF2N4O4
Molecular Weight
595.04
References & Citations
[1]Yang W, et al. Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species. J Med Chem. 2020 Jul 9;63 (13) :7226-7242.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-172400FXIa-IN-16
HY-153817FXIa-IN-13
HY-151196FXIa-IN-10
HY-150682FXIa-IN-9
HY-168712FXIa-IN-15
HY-128889FXIa-IN-1
HY-144658FXIa-IN-8
HY-150519FXIa-IN-11
HY-157547FXIa-IN-14
HY-145354-01FXIa-IN-7

Alternative Products

CatalogName
GTR19189586-01FXIa-IN-6
T70458-01FXIa-6f
MBS5805510FXIa-IN-7
GTR19184454-01FXIa-IN-8
GTR19241033-01FXIa-IN-15
GTR19274613-01FXIa-IN-17
MBS5806760FXIa-IN-10
T206453-01FXIa-IN-16
T64099-01FXIa-IN-9
T11341-01FXIa-IN-1

Popular Products