FXIa-IN-8
CAT:
804-HY-144658
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FXIa-IN-8
- CAS Number: 2744293-04-5
- UNSPSC Description: FXIa-IN-8 is a potent and selective FXIa inhibitor with an IC50 of 14.2 nM. FXIa-IN-8 shows antithrombotic activity without increasing the bleeding risk and obvious toxicitysup>[1].
- Target Antigen: Factor Xa
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/fxia-in-8.html
- Solubility: 10 mM in DMSO
- Smiles: ClC1=CC(/C=C/C(N[C@H](C(NC2=CC=C(C=C2)C(O)=O)=O)CC(N3CCN(CC3)C4=CC=CC=C4)=O)=O)=C(C=C1)N5C=NN=N5
- Molecular Weight: 629.07
- References & Citations: [1]Yao N, et al. Targeting the S2 Subsite Enables the Structure-Based Discovery of Novel Highly Selective Factor XIa Inhibitors. J Med Chem. 2022; 65(5):4318-4334.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported