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FXIa-IN-7

CAT:
804-HY-145354-03
Size:
25 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
FXIa-IN-7 - image 1

FXIa-IN-7

  • CAS Number: 2488952-56-1
  • UNSPSC Description: FXIa-IN-7 is a selective and orally bioavailable factor XIa inhibitor with an IC50 value of 0.4 nM.
  • Target Antigen: Factor Xa
  • Type: Reference compound
  • Related Pathways: Metabolic Enzyme/Protease
  • Applications: Neuroscience-Neuromodulation
  • Field of Research: Cardiovascular Disease
  • Assay Protocol: https://www.medchemexpress.com/fxia-in-7.html
  • Solubility: 10 mM in DMSO
  • Smiles: O=C(C1=CC=CC2=C1N(C[C@H](C3=CC(C(C)C)=CC(C4=CC=C(OC[C@H]5N)C5=C4)=C3)O)C=C2)O
  • Molecular Weight: 456.53
  • References & Citations: [1]Lorthiois E, et al. Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J Med Chem. 2020 Aug 13;63(15):8088-8113.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported