FXIa-IN-7

• UNSPSC Description:

  FXIa-IN-7 is a selective and orally bioavailable factor XIa inhibitor with an IC50 value of 0.4 nM.

• Target Antigen:

  Factor Xa

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/fxia-in-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=CC2=C1N(C[C@H](C3=CC(C(C)C)=CC(C4=CC=C(OC[C@H]5N)C5=C4)=C3)O)C=C2)O

• Molecular Weight:

  456.53

• References & Citations:

  [1]Lorthiois E, et al. Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J Med Chem. 2020 Aug 13;63(15):8088-8113.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2488952-56-1