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FXIa-IN-7

CAT: 0804-HY-145354-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145354-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FXIa-IN-7 is a selective and orally bioavailable factor XIa inhibitor with an IC50 value of 0.4 nM.
CAS Number
2488952-56-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fxia-in-7.html
Purity
98.59
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC2=C1N(C[C@H](C3=CC(C(C)C)=CC(C4=CC=C(OC[C@H]5N)C5=C4)=C3)O)C=C2)O
Molecular Formula
C28H28N2O4
Molecular Weight
456.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Lorthiois E, et al. Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J Med Chem. 2020 Aug 13;63 (15) :8088-8113.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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