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FXIa-IN-10

CAT:
804-HY-151196
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
FXIa-IN-10 - image 1

FXIa-IN-10

  • CAS Number: 2816108-08-2
  • UNSPSC Description: FXIa-IN-10 (Compound 3f) is a potent activated factor XI (FXIa) inhibitor with an Ki of 0.17 nM. FXIa-IN-10 has good oral bioavailability[1].
  • Target Antigen: Others
  • Type: Reference compound
  • Related Pathways: Others
  • Applications: Neuroscience-Neuromodulation
  • Field of Research: Cardiovascular Disease
  • Assay Protocol: https://www.medchemexpress.com/fxia-in-10.html
  • Solubility: 10 mM in DMSO
  • Smiles: CN1N=NC=C1C2=CN([C@@H](C3=CC=C(C4=C(N5N=NC(Cl)=C5)C=CC(Cl)=C4F)C=[N+]3[O-])CCOC(F)F)N=C2
  • Molecular Weight: 580.35
  • References & Citations: [1]Xu G, et al. Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions. J Med Chem. 2022 Aug 11;65(15):10419-10440.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported