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FXIa-IN-9

CAT: 0931-T64099-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64099-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2816108-87-7
Target
Others, Factor Xa
Related Pathways
Metabolism, Others
Bioactivity
FXIa-IN-9 (compound 3f) is a potent, selective inhibitor of FXIa, demonstrating strong binding affinity through hydrogen bond formation (human FXIa Ki: 0.17 nM, rabbit FXIa Ki: 0.5 nM) . It exhibits anticoagulant properties, making it valuable for research into thromboembolic conditions, including atrial fibrillation, stroke, myocardial infarction, deep vein thrombosis, and pulmonary embolism [1].
Smiles
FC=1C(=C(C=CC1Cl)N2N=NC(Cl)=C2)C3=CN(=O)=C(C(CCOC(F)F)N4C=C(C=N4)C=5N(C)N=NC5)C=C3
Molecular Formula
C23H18Cl2F3N9O2
Molecular Weight
580.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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