FXIa-IN-6

• Target:

  Factor Xa|||Others

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most relevant serine proteases (K_i = 0.3 nM), demonstrating excellent pharmacokinetics (PK) profile, including high oral bioavailability and low clearance, in multiple preclinical species.

• Smiles:

  N(C(OC)=O)C=1C=C2C(C=3C=C([C@@H](CCC[C@@H](C)C(=O)N2)N4C(=O)C=C(CC4)C5=C(F)C(Cl)=CC=C5F)N=CC3)=CC1

• Molecular Formula:

  C31H29ClF2N4O4

• Molecular Weight:

  595.04

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1551460-43-5