Win 58237

• Description :

  Win 58237 is a cyclic nucleotide phosphodiesterase (PDE) inhibitor, with Ki of 170 nM for PDE V, possessing vasorelaxant activity.

• UNSPSC :

  12352005

• Target :

  Phosphodiesterase (PDE)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/Win_58237.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=C(N(C3CCCC3)N=C2C)NC(C4=CC=NC=C4)=N1

• Molecular Formula :

  C16H17N5O

• Molecular Weight :

  295.34

• References & Citations :

  [1]Silver PJ, et al. Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor. J Pharmacol Exp Ther. 1994 Dec;271 (3) :1143-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [158001-76-4]