Win 58237

CAT: 0804-HY-101661Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-101661Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Win 58237 is a cyclic nucleotide phosphodiesterase (PDE) inhibitor, with Ki of 170 nM for PDE V, possessing vasorelaxant activity.
CAS Number
[158001-76-4]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Win_58237.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N(C3CCCC3)N=C2C)NC(C4=CC=NC=C4)=N1
Molecular Formula
C16H17N5O
Molecular Weight
295.34
References & Citations
[1]Silver PJ, et al. Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor. J Pharmacol Exp Ther. 1994 Dec;271 (3) :1143-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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