Win 45164

• Description :

  Win 45164 is an orally active glucocorticoid receptor (Glucocorticoid Receptor) ligand with the activity of inhibiting the pituitary - adrenal axis. It can promote liver glycogen deposition and thymus involution in adrenalectomized male rats. Meanwhile, Win 45164 has anti - inflammatory effects. It can be used in the research of inflammatory and neurological diseases[1].

• UNSPSC :

  12352005

• Target :

  Glucocorticoid Receptor

• Related Pathways :

  Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Smiles :

  O=C(C1CC=C2C(C1C(C)=O)CCC3=CC4=C(CC32C)C=NN4C5=CC=C(C=C5)F)C

• Molecular Formula :

  C26H27FN2O2

• Molecular Weight :

  418.50

• References & Citations :

  [1]Schane HP, et al. Glucocorticoid/antiinflammatory activities of nonsteroidal phenylpyrazoles in the rat. Steroids. 1985 Feb;45 (2) :171-85.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [83880-39-1]