WIN 51708

• Description :

  WIN 51708 is a nonpeptide antagonist of neurokinin (NK) -1 receptor. WIN 51708 has a higher affinity for the rat NK-1 receptor compared to the human NK-1 receptor[1].

• UNSPSC :

  12352005

• Target :

  Neurokinin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/win-51708.html

• Smiles :

  C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])CC4=NC5=NC6=CC=CC=C6N5C=C4C2)([H])[C@@]7([H])[C@](CC3)([C@@](O)(CC7)C#C)C

• Molecular Formula :

  C29H33N3O

• Molecular Weight :

  439.59

• References & Citations :

  [1]Sachais BS, et al. Both extracellular and transmembrane residues contribute to the species selectivity of the neurokinin-1 receptor antagonist WIN 51708. Mol Pharmacol. 1994 Jul;46 (1) :122-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [144177-30-0]