WIN 51708

CAT: 0804-HY-105346-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-105346-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WIN 51708 is a nonpeptide antagonist of neurokinin (NK) -1 receptor. WIN 51708 has a higher affinity for the rat NK-1 receptor compared to the human NK-1 receptor[1].
CAS Number
[144177-30-0]
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/win-51708.html
Smiles
C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])CC4=NC5=NC6=CC=CC=C6N5C=C4C2)([H])[C@@]7([H])[C@](CC3)([C@@](O)(CC7)C#C)C
Molecular Formula
C29H33N3O
Molecular Weight
439.59
References & Citations
[1]Sachais BS, et al. Both extracellular and transmembrane residues contribute to the species selectivity of the neurokinin-1 receptor antagonist WIN 51708. Mol Pharmacol. 1994 Jul;46 (1) :122-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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