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Methyltetrazine-PEG8-NHS ester

CAT: 0804-HY-141270-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-141270-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-PEG8-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
CAS Number
2183440-34-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.25
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOC2=CC=C(C3=NN=C(C)N=N3)C=C2
Molecular Formula
C32H47N5O13
Molecular Weight
709.74
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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