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Win 47338

CAT: 0804-HY-W100186-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W100186-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Win 47338 (compound 14) is a control compound of inhibitors of the mitotic kinase monopolar spindle MPS1 and Aurora kinases (AurA/AurB) (Ki>100 μM) [1].
CAS Number
80047-24-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Aurora Kinase
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Others
Smiles
O=C(C1=CC(C2=CC=NC=C2)=C(C)NC1=O)N
Molecular Formula
C12H11N3O2
Molecular Weight
229.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Fearon D, et al. Synthesis and profiling of a 3-aminopyridin-2-one-based kinase targeted fragment library: Identification of 3-amino-5- (pyridin-4-yl) pyridin-2 (1H) -one scaffold for monopolar spindle 1 (MPS1) and Aurora kinases inhibition. Bioorg Med Chem. 2018 Jul 15;26 (11) :3021-3029.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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