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Apoptosis inducer 26

CAT: 0804-HY-162819Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162819Size:1 Each
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Description
Apoptosis inducer 26 (compound [AgCl (dap2SH) (PPh3) 2]) is an autophagy inducer based on mononuclear Ag (I) ligands, with antibacterial and anticancer activities against a variety of bacterial strains and cancer cell lines. Apoptosis inducer 26 can effectively inhibit the growth of both Gram (+) and Gram (-) bacteria by causing the accumulation of Ag (I) ions in the bacterial periplasm. Apoptosis inducer 26 can intercalate between base pairs of CT DNA and induce apoptosis in A549 cells. Apoptosis inducer 26 also has the ability to scavenge free radicals, which can protect against oxidative stress[1].
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-26.html
Smiles
NC1=NC(NC(N)=C1)=[S][Ag]([P](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)([P](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)Cl
Molecular Formula
C40H36AgClN4P2S
Molecular Weight
810.07
References & Citations
[1]Amine-substituted heterocyclic thioamide Cu (I) and Ag (I) complexes as effective anticancer and antibacterial agents targeting the periplasm of E. coli bacteria
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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