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Antitumor agent-129

CAT: 0804-HY-162121Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162121Size:1 Each
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Description
Antitumor agent-129 (Compound 68) is a thiazolidin-4-one sulfone derivative and an Osteosarcoma (OS) inhibitor with an IC50 value of 0.217 μM, a half-life of 73.8 min (mouse liver microsome) and an excellent pharmacokinetic profile (in vivo bioavailability F = 115%, intraperitoneal administration) . Antitumor agent-129 is a potential candidate for OS research[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-129.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCCOC)C1=NC(C2N(C3=NC=CC=C3OC)C(CS2(=O)=O)=O)=CC=C1
Molecular Formula
C20H24N4O6S
Molecular Weight
448.49
References & Citations
[1]Xuwen Chen, et al. Discovery of potent thiazolidin-4-one sulfone derivatives for inhibition of proliferation of osteosarcoma in vitro and in vivo, European Journal of Medicinal Chemistry, 2024, 116082, ISSN 0223-5234.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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