JAK1/TYK2-IN-4
CAT:
804-HY-161019
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JAK1/TYK2-IN-4
- CAS Number: 2734918-33-1
- UNSPSC Description: JAK1/TYK2-IN-4 is a dual inhibitor of JAK and TYK2, with IC50s of 39 nM and 21 nM, respectively. JAK1/TYK2-IN-4 has oral bioavailability[1].
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/jak1-tyk2-in-4.html
- Solubility: 10 mM in DMSO
- Smiles: CC1=C(N2CCC3(C(NCC3)=O)CC2)N=C(NC4=CN(C)N=C4)N=C1
- Molecular Weight: 341.41
- References & Citations: [1]Xue Cui, et al. Therapeutic potential of a synthetic dual JAK1/TYK2 inhibitor in inflammatory bowel disease. Int Immunopharmacol. 2023 Nov 20:126:111238.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported