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JAK1/TYK2-IN-3

CAT: 0931-T64265-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64265-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, JAK
Related Pathways
Angiogenesis, Others, Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic, JAK/STAT signaling
Bioactivity
JAK1/TYK2-IN-3 is a selective, potent, orally active dual inhibitor of TYK2 (IC50: 6 nM) and JAK1 (IC50: 37 nM), with selective action on JAK2 (IC50: 140 nM) and JAK3 (IC50: 362 nM) . It regulates the expression of TYK2/JAK1-related genes and formation of Th1, Th2, and Th17 cells to exert anti-inflammatory activity.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-143885JAK1/TYK2-IN-3
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A21982-25Tyk2-IN-3 25mg
A21982-1Tyk2-IN-3 1mg
A21982-10Tyk2-IN-3 10mg
A21982-100Tyk2-IN-3 100mg

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