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Tyk2-IN-20

CAT: 0804-HY-168269Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168269Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tyk2-IN-20 (Example 289) is a potent Tyk2 inhibitor with an IC50 of JAK1, JAK2, and JAK3 with IIC50 values of [1].
CAS Number
3058568-08-1
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tyk2-in-20.html
Smiles
C[C@@H]([C@@](C#N)(C1CC1)C2=O)CN2C3=NC(C4=CN(C5CC6(COC6)C5)N=C4)=CN7C3=CC=N7
Molecular Formula
C24H25N7O2
Molecular Weight
443.50
References & Citations
[1]Nathan Edward GENUNG, et al. 1h-pyrrolo[2,3-b]pyridin-4-yl]-2-oxopyrrolidine-3-carbonitrile derivatives as tyrosine kinase 2 (tyk2) inhibitors for the treatment of inflammatory diseases. WO2024211696A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK1; JAK2; JAK3; Tyk2

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