Tyk2-IN-3

CAT: 0804-HY-18709Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-18709Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Tyk2-IN-3 is a Tyk2 pseudokinase inhibitor, with an IC50 of 485 nM.
CAS Number
[1779493-12-7]
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Tyk2-IN-3.html
Solubility
10 mM in DMSO
Smiles
CN1C=NC2=C1C(N=C(C3=CC=CC([C@@H](C)NC(C4=C(S(=O)(C)=O)C=CC=C4)=O)=C3)S5)=C5N=C2NC
Molecular Formula
C25H24N6O3S2
Molecular Weight
520.63
References & Citations
[1]Tokarski JS, et al. Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. J Biol Chem. 2015 Apr 24;290 (17) :11061-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Tyk2

Related Products

CatalogName
HY-163305Tyk2-IN-17
HY-161683-01Tyk2-IN-19
HY-126242S-01Tyk2-IN-7
HY-163304Tyk2-IN-16
HY-144087TYK2-IN-11
HY-163303Tyk2-IN-15
HY-168269Tyk2-IN-20
HY-138317Tyk2-IN-10
HY-101762-01TyK2-IN-2
HY-178913Tyk2-IN-23

Alternative Products

CatalogName
MBS5767797Tyk2-IN-3
MBS5806925JAK1/TYK2-IN-3
A21982-1Tyk2-IN-3 1mg
A21982-25Tyk2-IN-3 25mg
A21982-10Tyk2-IN-3 10mg
A21982-5Tyk2-IN-3 5mg
A21982-50Tyk2-IN-3 50mg
A21982-100Tyk2-IN-3 100mg
MBS8561961-01TYK2
M11333-01Tyk2-IN-30

Popular Products