Tyk2-IN-3
CAT:
804-HY-18709
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Tyk2-IN-3
- CAS Number: 1779493-12-7
- UNSPSC Description: Tyk2-IN-3 is a Tyk2 pseudokinase inhibitor, with an IC50 of 485 nM.
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/Tyk2-IN-3.html
- Solubility: 10 mM in DMSO
- Smiles: CN1C=NC2=C1C(N=C(C3=CC=CC([C@@H](C)NC(C4=C(S(=O)(C)=O)C=CC=C4)=O)=C3)S5)=C5N=C2NC
- Molecular Weight: 520.63
- References & Citations: [1]Tokarski JS, et al. Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. J Biol Chem. 2015 Apr 24;290(17):11061-74.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported