TYK2-IN-11

TYK2-IN-11

• CAS Number: 2757009-40-6
• UNSPSC Description: TYK2-IN-11 (Compound 5B) is a selective Tyk-2 inhibitor with IC50s of 0.016 and 0.31 nM for TYK2-JH2 and JAK1-JH2, respectively. TYK2-IN-11 can be used for the research of inflammatory or autoimmune disease[1].
• Target Antigen: JAK
• Type: Reference compound
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/tyk2-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C)NC1=CC(NC2=CC=CC(S(=O)(C)=O)=N2)=C(C3=NC=CC=C3)C=N1
• Molecular Weight: 383.42
• References & Citations: [1]Qiuwen WANG, et al. Tyk-2 inhibitor. WO2021259208A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported