Products for Research Use Only
RegisterLogin

Gcase activator 3

CAT: 0804-HY-160426-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-160426-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Gcase activator 3 (compound 9Q) is a glucosidase (Glucosidase, GCase) activator that can partially stabilize GCase and increase its activity. Gcase activator 3 reduces mutant GCase protein misfolding and degradation in fibroblasts and dopaminergic midbrain neurons. Gcase activator 3 can be used in the study of Parkinson's disease (PD) and related synucleinopathies[1].
CAS Number
2270984-21-7
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gcase-activator-3.html
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(C[C@@H]1OC2=CC=CC=C2OC1)C3=C4C=CC=CC4=NC(C5=CC=CN=C5)=N3
Molecular Formula
C23H20N4O2
Molecular Weight
384.43
References & Citations
[1]Zheng J, et al. Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase. J Med Chem. 2019 Feb 14;62 (3) :1218-1230.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-154823-01Gcase activator 2
HY-156287-01GCase modulator-1
HY-155390Caspase-3 activator 3
HY-147397PKM2 activator 3
HY-144287-01Glucokinase activator 3
HY-143333-01Nrf2 activator-3
HY-179539ISR activator 3
HY-174145GLUT4 activator 3
HY-151203PKG1α activator 3
HY-161725-01TFEB activator 3

Alternative Products

CatalogName
T86495-01Gcase activator 2
T86496-01Gcase activator 3
T4280-01Gcase activator 1
GTR19217665-01GCase modulator-1
YP-W23209-01Mouse glucocerebrosidase (GCase) ELISA Kit
YP-W18614-01Human glucocerebrosidase (GCase) ELISA Kit
A03553-100Lysosomal acid GCase Antibody, mAb, Rabbit
CST 88162TGCase/GBA (E2R1L) Rabbit Monoclonal Antibody
E49Y6742Lysosomal acid GCase Rabbit Monoclonal Antibody
T22567AMPK activator

Popular Products