Caspase-3 activator 3

Caspase-3 activator 3

• CAS Number: 2999724-54-6
• UNSPSC Description: Caspase-3 activator 3 (compound 2h) induces apoptosis in HL-60 and K562 cells via significant caspase 3 activation. Caspase-3 activator 3 shows antileukemic acticity against HL-60 and K562 cells, with IC50 values of 42.89 and 33.61 μM, respectively[1].
• Target Antigen: Apoptosis; Caspase
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/caspase-3-activator-3.html
• Solubility: 10 mM in DMSO
• Smiles: CN1CCN(C2=CC=C(C3CC(C4=CSC=C4)=NN3C5=CC=CC(Br)=C5)C=C2)CC1
• Molecular Weight: 481.45
• References & Citations: [1]Mehlika Dilek Altıntop, et al. Design, Synthesis, and Evaluation of a New Series of 2-Pyrazolines as Potential Antileukemic Agents. ACS Omega 2023.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported