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PPARγ modulator-1

CAT: 0804-HY-160159Size: 1 EachDry Ice: NoHazardous: No
CAT#: HY-160159Size: 1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anticancer agent 183 (example 48) is a non-agonistic PPARG modulator. Anticancer agent 183 has a high affinity to PPARG (PPARγ) . Anticancer agent 183 inhibits kinase-mediated phosphorylation of PPARG. Anticancer agent 183 can used for research on metabolic diseases to avoid side effects[1].
CAS Number
[1415321-54-8]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparγ-modulator-1.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](C1=CC=C(C=C1)C(C)(C)C)NC(C2=CC=C(C(C(C)=C3C)=C2)N3CC4=CC(OC(C)(C)C(O)=O)=CC=C4)=O
Molecular Formula
C34H40N2O4
Molecular Weight
540.69
References & Citations
[1]Theodore Mark Kamenecka, et al. N-benzylindole modulators of pparg. 2012.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ

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