PPARγ modulator-1

• Description :

  Anticancer agent 183 (example 48) is a non-agonistic PPARG modulator. Anticancer agent 183 has a high affinity to PPARG (PPARγ) . Anticancer agent 183 inhibits kinase-mediated phosphorylation of PPARG. Anticancer agent 183 can used for research on metabolic diseases to avoid side effects[1].

• UNSPSC :

  12352005

• Target :

  PPAR

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/pparγ-modulator-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@H](C1=CC=C(C=C1)C(C)(C)C)NC(C2=CC=C(C(C(C)=C3C)=C2)N3CC4=CC(OC(C)(C)C(O)=O)=CC=C4)=O

• Molecular Formula :

  C34H40N2O4

• Molecular Weight :

  540.69

• References & Citations :

  [1]Theodore Mark Kamenecka, et al. N-benzylindole modulators of pparg. 2012.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PPARγ

• CAS Number :

  [1415321-54-8]