PPARα/γ/δ agonist 1
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PPARα/γ/δ agonist 1
Description:
PPARα/γ/δ agonist 1 (Compound 2) is a potent PPARα/γ/δ agonist, with an IC50 of 70 nM for PPARγ. PPARα/γ/δ agonist 1 can be used for the research of type 2 diabetes[1].UNSPSC:
12352005Hazard Statement:
H302-H315-H319-H335Target:
PPARRelated Pathways:
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear ReceptorField of Research:
Metabolic DiseaseSmiles:
O=C(CN1C=CC2=C1C=CC(OCCCOC3=C(CCC)C4=CC=C(C(C5=CC=CC=C5)=O)C=C4C=C3)=C2)OMolecular Formula:
C33H31NO5Molecular Weight:
521.60Precautions:
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501References & Citations:
[1]Mahindroo N, et al. Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists. J Med Chem. 2006 Oct 19;49 (21) :6421-4.Shipping Conditions:
Room temperatureScientific Category:
Reference compound1Clinical Information:
No Development ReportedCAS Number:
[853652-40-1]
