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ABP/PPAR modulator 1

CAT: 0013-GTR19258268-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258268-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABP/PPAR modulator 1 is an orally active multi-regulator of FABP and PPAR, exhibiting IC50 values of 0.65 μM for FABP1 and 1.08 μM for FABP4, and EC50 values of 9.19 μM, 2.20 μM, and 1.58 μM for PPARα, PPARγ, and PPARδ, respectively. It demonstrates potent activity against metabolic dysfunction-associated steatohepatitis (MASH) . Additionally, ABP/PPAR modulator 1 dose-dependently improves various pathological features of fatty liver in a WD + Carbon tetrachloride-induced MASH mouse model.
Field of Research
Metabolism Research, Molecular Biology
Smiles
COC1=CC=C (/C=C/C2=CC (OC) =CC (OCC3=CC=C (OC (C (N[C@@H] (C (O) =O) CC (C) C) =O) (C) C) C=C3) =C2) C=C1
Molecular Formula
C33H39NO7
Molecular Weight
561.67
Storage Conditions
-20°C
Notes
For research use only.

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