NMS-P528

• Description :

  NMS-P528 is a Duocarmycin derivative that can be used as an ADC payload. NMS-P528 can be used to synthesize NMS-P945[1].

• UNSPSC :

  12352203

• Target :

  ADC Payload

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/nms-p528.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC[C@@H](C1=C2C=C(O)C3=C1C(C)=CS3)CN2C(C(N4)=CC5=C4C=CC(OCCN6CCCC6)=C5)=O

• Molecular Formula :

  C27H28ClN3O3S

• Molecular Weight :

  510.05

• References & Citations :

  [1]Barbara Valsasina, et al. Novel thienoduocarmycin-trastuzumab ADC demonstrates Strong Anti-tumor Efficacy with Favorable Safety Profile in Preclinical Studies. Mol Cancer Ther. 2023 Sep 19.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• CAS Number :

  [1466546-45-1]