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NMS-P945

CAT: 0804-HY-156299Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156299Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NMS-P945 is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs) . NMS-P945 is suitable for conjugation to mAbs with reproducible Drug Antibody Ratio (DAR) >3.5[1].
CAS Number
1466546-35-9
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nms-p945.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N(C)CCN(C)C(OC(C3=C4C(C)=CS3)=CC5=C4[C@H](CCl)CN5C(C6=CC(C=C(C=C7)OCCN8CCCC8)=C7N6)=O)=O)=O)C=C2)=O)=O)=O)C=CC1=O
Molecular Formula
C61H76ClN11O12S
Molecular Weight
1222.84
References & Citations
[1]Valsasina B, Novel thienoduocarmycin-trastuzumab ADC demonstrates Strong Anti-tumor Efficacy with Favorable Safety Profile in Preclinical Studies. Mol Cancer Ther. 2023 Sep 19.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported

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