Antitumor agent-103

• UNSPSC Description:

  Antitumor agent-103 (compound 24l) is an apoptosis inducer with antiproliferative and anti-clony formation activities. Antitumor agent-103 arrests cell cycle at G0/G1 phase, enhances NO production, and exhibits anti-tumor activity[1].

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-103.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCN(CC1)CCOC2=NO[N+]([O-])=C2S(=O)(C3=CC=CC=C3)=O)CSC4=NC(C5=CC=CC=C5)=C(C#N)C(NC6=CC(OC)=C(OC)C(OC)=C6)=N4

• Molecular Weight:

  788.85

• References & Citations:

  [1]Chi L, et al. Design, synthesis and biological evaluation of nitric oxide-releasing 5-cyano-6-phenyl-2, 4-disubstituted pyrimidine derivatives. Bioorg Med Chem Lett. 2023 Aug 15;92:129389.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4