Trypanothione synthetase-IN-2

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804-HY-151150

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UNSPSC Description: Trypanothione synthetase-IN-2 (Compound 3) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 5.4 μM when triamine spermidine is as polyamine S[1].
Target Antigen: Parasite
Type: Reference compound
Related Pathways: Anti-infection
Applications: COVID-19-immunoregulation
Field of Research: Infection
Assay Protocol: https://www.medchemexpress.com/trypanothione-synthetase-in-2.html
Solubility: 10 mM in DMSO
Smiles: CCCCCCCCCCCC(NC(COC(C1=CC(OCCN)=C(C(OCCN)=C1)OCCN)=O)COC(C2=CC(OCCN)=C(C(OCCN)=C2)OCCN)=O)=O
Molecular Weight: 836.03
References & Citations: [1]Alcón-Calderón M, et al. Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library. European Journal of Medicinal Chemistry, 2022: 114675.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-151150	Trypanothione synthetase-IN-2
HY-151149	Trypanothione synthetase-IN-4
HY-162134	Trypanothione synthetase-IN-5
HY-151151	Trypanothione synthetase-IN-3
HY-151148	Trypanothione synthetase-IN-1
HY-148205	Trypanothione
HY-147674	Isoleucyl tRNA synthetase-IN-2
HY-147643	Aminoacyl tRNA synthetase-IN-2
HY-152149-06	CTP Synthetase-IN-1
HY-152149-05	CTP Synthetase-IN-1

Cat	Name
T64056-1g	Trypanothione synthetase-IN-4
T64056-10mg	Trypanothione synthetase-IN-4
T64056-50mg	Trypanothione synthetase-IN-4
T64056-1mg	Trypanothione synthetase-IN-4
T64056-5mg	Trypanothione synthetase-IN-4
MBS1094207-02	Recombinant Trypanothione synthetase (TRS), partial
MBS1094207-03	Recombinant Trypanothione synthetase (TRS), partial
MBS1094207-04	Recombinant Trypanothione synthetase (TRS), partial
MBS1094207-01	Recombinant Trypanothione synthetase (TRS), partial
MBS1094207-05	Recombinant Trypanothione synthetase (TRS), partial