Trypanothione synthetase-IN-2
CAT:
804-HY-151150
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Trypanothione synthetase-IN-2
UNSPSC Description:
Trypanothione synthetase-IN-2 (Compound 3) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 5.4 μM when triamine spermidine is as polyamine S[1].Target Antigen:
ParasiteType:
Reference compoundRelated Pathways:
Anti-infectionApplications:
COVID-19-immunoregulationField of Research:
InfectionAssay Protocol:
https://www.medchemexpress.com/trypanothione-synthetase-in-2.htmlSolubility:
10 mM in DMSOSmiles:
CCCCCCCCCCCC(NC(COC(C1=CC(OCCN)=C(C(OCCN)=C1)OCCN)=O)COC(C2=CC(OCCN)=C(C(OCCN)=C2)OCCN)=O)=OMolecular Weight:
836.03References & Citations:
[1]Alcón-Calderón M, et al. Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library. European Journal of Medicinal Chemistry, 2022: 114675.Shipping Conditions:
Room temperatureClinical Information:
No Development Reported