Trypanothione synthetase-IN-2

CAT:
804-HY-151150
Size:
Inquire
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Trypanothione synthetase-IN-2 - image 1

Trypanothione synthetase-IN-2

  • UNSPSC Description:

    Trypanothione synthetase-IN-2 (Compound 3) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 5.4 μM when triamine spermidine is as polyamine S[1].
  • Target Antigen:

    Parasite
  • Type:

    Reference compound
  • Related Pathways:

    Anti-infection
  • Applications:

    COVID-19-immunoregulation
  • Field of Research:

    Infection
  • Assay Protocol:

    https://www.medchemexpress.com/trypanothione-synthetase-in-2.html
  • Solubility:

    10 mM in DMSO
  • Smiles:

    CCCCCCCCCCCC(NC(COC(C1=CC(OCCN)=C(C(OCCN)=C1)OCCN)=O)COC(C2=CC(OCCN)=C(C(OCCN)=C2)OCCN)=O)=O
  • Molecular Weight:

    836.03
  • References & Citations:

    [1]Alcón-Calderón M, et al. Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library. European Journal of Medicinal Chemistry, 2022: 114675.
  • Shipping Conditions:

    Room temperature
  • Clinical Information:

    No Development Reported