Aminoacyl tRNA synthetase-IN-2

• UNSPSC Description:

  Aminoacyl tRNA synthetase-IN-2 (Compound 14) is an aminoacyl-tRNA synthetase (aaRS) inhibitor. Aminoacyl tRNA synthetase-IN-2 can be used for development of a new family of antibiotics[1].

• Target Antigen:

  Aminoacyl-tRNA Synthetase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/aminoacyl-trna-synthetase-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)[C@H](NC([C@@H](N)CO)=O)[C@@H]([C@@H]1[C@H](O)[C@@H](O)[C@H](N(C(N2C)=O)C=CC2=O)S1)O

• Molecular Weight:

  434.42

• References & Citations:

  [1]Gadakh B, et al. Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase. Bioorg Med Chem. 2020 Sep 1;28(17):115645.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  93218-59-8